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讲座信息
过时的故事
发布时间:2011-10-28      点击量:1900
主讲人:顾孝诚
讲座地点:北大新生物楼101室邓祐才报告厅
讲座日期:2011-04-15
 

Degrees, Qualifications:

  • 1984-1985 Visitor, in Department of Biological Chemistry, Harvard Medical School
  • 1961-1964 Advanced training on Protein Crystallography in Department of Chemistry, Peking University
  • 1948-1952 Graduated from the Department of Plant Sciences, Peking University

Work Experience

  • 1995- present : Professor emeritus, College of Life Sciences, Peking University
  • 1995 - 2005 : Coordinator, CUSBA Program
  • 1997 - 2004 : Chairperson, Council of Scientific Advisors, ICGEB
  • 1994 - 2004 : Chairperson, Council of Academic Committee, National Laboratory of Protein Engineering and Plant Genetic Engineering, Peking University?
  • 1995 - 1997 : Member, Council of Scientific Advisors, ICGEB (International Center for Genetic Engineering and Biotechnology)
  • 1992 - 1995 : Professor of Biophysics, College of life Sciences, Peking University
  • 1986 - 1995 : Member and Director of the Evaluation Group for Section of Biochemistry and Molecular Biology, the Chinese National Science Foundation
  • 1986 - 1995 : Member,. Working Group for establishment of the Biotechnology Area in the National High Technology and Development (863) Program; Director, Experts Group for Section of Protein Engineering, 863 Program ; Member, Experts Committee for the Biotechnology Area, 863 Program
  • 1952 - 1995 : Teaching assistant, lecturer, associate professor and professor in Department of Biology, Peking University
  • 1987 - 1994 : Director, National Laboratory of Protein Engineering and Plant Genetic Engineering, Peking University
  • 1985 - 1992 : Chairperson, Department of Biology, Peking University
  • 1981 - 1989 : Coordinator, CUSBEA Program for Ministry of Education
  • 1978 - 1984 : Deputy chairperson, Department of Biology, Peking University

National Honors and Awards

  • 2000 : National First Prize for Excellent Performance in the Biotechnology Area of the 863 Program, from the Ministry of Science and Technology
  • 1994 : The Golden Ox Prize of the State Planning Commission for the National Laboratory of Protein Engineering and Plant Genetic Engineering, Peking University?
  • 1993 : National Second Prize for Excellent Performance in the Biotechnology Area of the 863 Program, from the Ministry of Science and Technology
  • 1991 : National Award for Excellent Performance in the Biotechnology Area of the 863 Program, from the Ministry of Science and Technology
  • 1990 : The Golden Ox Prize of the State Planning Commission, for the National Laboratory of Protein Engineering and Plant Genetic Engineering, Peking University
  • 1989 : Listed in the International Who is Who
  • 1986 : First Prize for Progress in Science and Technology from the Ministry of Education ; Studies on the Biology of the Giant Panda (Group Award)
  • 1982 : National Second Prize for Natural Science Research : Crystal Structure Analysis of the Rhombohedral 2 Zinc Porcine Insulin Molecule (Group Award)
  • 1979 : National 3-8 Award for Career Women
  • 1978 : National Award from the National Congress of Science and Technology, for "Crystal Analysis of the Insulin Molecule" (Group Award)

Publications

1. The Insulin Structure Group?The Rhombohedral 2 Zinc Porcine Insulin Molecule at 1.8 Angstrom Resolution, (1974), Scientia Sinica restarted, Vol.1

2. "Protein Engineering" Gu Xiaocheng inEd: Gu Xiaocheng (1994)?Shanghai Science andTechnology Press

3. "Protein Engineering" Gu Xiaocheng inEdited by Zhu Lilan, Vice Minister of the Ministry of Science and Technology and Foreword by BB Ghali, Secretary General of the UN (1995) LiaoNing Press

4. YX Qu, SP Liang,JZ Ding, L Ma, RJ Zhang, XC Gu, Proton Nuclear Magnetic Resonance Studies on Huwentoxin I from the Venom of the Spider Selenocosmia huwena : Sequence specific H-NMR Assignments 1995 J Prot. Chem. 14 : 549-557

5. YX Qu, SP Liang,JZ Ding, XC Liu, RJ Zhang, XC Gu, Proton Nuclear Magnetic Resonance Studies on Huwentoxin-I from the Venom of the Spider Selenocosmia huwena.: 2 Three Dimensional Structure in Solution 1996 J Prot. Chem 16: 565-574

6. J Zhang, ZQ Hua, JRH Tame, GY Lu, RJ Zhang, XC Gu, The Crystal Structure of High Oxygen Affinity Species of Haemoglobin (Bar-Headed Goose Haemoglobin : The Oxy Form ) 1996 J Mol. Biol. 255 : 484-493

7. GY Lu, ZH Zhou, ML Breiber, J Jakana, DY Cai, XC Wei, SC Chen, XC Gu, W Chiu,, Structure of Double-Shelled Rice Dwarf Virus, 1998, J Virol, 72 : 8541-8546

8. SY Lu, SP Liang,XC Gu, Three dimensional Structure of Selenocosmia huwena Lectin-I (SHL-I) From the Venom of the Spider Selencosmia huwena by 2D NMR, 1999, J Prot Chem.18 : 609-617

9. SY Lu, PC Deng, XC Liu, JC Luo, RS Han, XC Gu, SP Liang, XC Wang, F Li, V Lozanov, A Patthy, S Pongor, Solution Structure of the Major-Alpha-Amylase Inhibitor of the Crop Plant Amaranth, 1999, J Biol. Chem. 274 : 20473-20478

10. HT Ding, H Ren, Q Chen, G Fang, LF Li, R Li, Z Wang, XY Jia, YH Liang, MH Hu, Y Li, JC Luo, XC Gu, XD Su, M Luo, SY Lu, Parallel Cloning, Expression, Purification and Crystallization of Human Proteins for Structural Genomics, 2002, Acta Cryst D58:2102-2108

11. DL Li,YC Xiao, X Xu, X Xiong, SY Lu, ZH Liu, Q Zhu, MC Wang, XC Gu, SP Liang, Structure-Activity Relationship of HinanToxin IV and Structure Determination of Active and Inactive Sodium Channel Blockers, 2004, J Biol. Chem. 279 : 37734-37740

12. XY Dai,Q Chen, M Lian, YZ Zhou, SY Lu, YJ Chen, JC Luo, XC Gu, Y Jiang, M Luo, XF ZhengSystematic High-yield Production of Human Secreted Proteins in E. Coli, 2005, BBRC 332 : 593-601

13. Q Chen, YH Liang,XD Su, XC Gu, XF Zheng, M Luo, Novel IMP Binding in Feedback Inhibition of Hypoxanthin Guanine Phosphoribosyl Transferase from Thermoanaerobacter tengcongensis, 2005, J Mol. Biol, 348 : 1199-1210

14. Guo A, He K, Liu D, Bai S, Gu X, Wei L, Luo J, DATF : A Database of Arabidopsis Transcription Factors, 2005, Bioinformatics, 21 : 2568-2569

15. Gao G, Zhang Y, Guo A, Zhu Q, Tang W, Zheng W, Gu X, Wei L, Luo J, DRTF: A Database of Rice Transcription Factors, 2006, Bioinformatics, 22 : 1286-1287

16. Xiaofeng Zheng, Xueyu Dai, Yanmei Zhao, Qiang Chen, Fei Lu, Deqiang Yao, Xinping Liu, Chuanmao Zhang, Xiaocheng Gu, Ming Luo, Restructuring of the Dinucleotide Binding Fold in a NADP(H) Sensor Protein, 2007, PNAS, 104 : 8809-8814

17. Chuan-Yun Li, Quan Yu, Zhi-Qiang Ye, Ying Sun, Quanyue He, Xiao_Mo Li, Wuxue Zhang, Jingchu Luo, Xiaocheng Gu, Xiaofeng Zheng, Liping Wei, A Nonsynonomous SNP in Human Cytosolic Sialidase in a Small Asian Population Results in Reduced Enzyme Activity : Potential Link with Severe Adverse Reactions to Oseltamivir, 2007, Cell Research, 17 : 357-362

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